Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.37 |
| ▸ | C1R | P00736 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14374834 | 0.81 | SMN1; SMN2 (0.49) | SMN1; SMN2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL14347638 | 0.80 | AHR (0.44) | KDM4EMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL14347584 | 0.78 | DAO (0.46) | KDM4EMEN1KMT2APARP1 | |
| SCHEMBL10220393 | 0.76 | KIF11 (0.47) | SMN1; SMN2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL14843175 | 0.75 | KIF11 (0.50) | SMN1; SMN2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL8251634 | 0.72 | KDM4E (0.53) | SMN1; SMN2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL31083618 | 0.72 | KIF11 (0.74) | SMN1; SMN2KDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL27951682 | 0.72 | DAO (0.46) | SMN1; SMN2KDM4EALDH1A1HSD17B10PARP1 | |
| SCHEMBL14347279 | 0.71 | MAPT (0.42) | SMN1; SMN2KDM4EMEN1LMNAHTT | |
| SCHEMBL32674536 | 0.70 | KDM4E (0.45) | SMN1; SMN2KDM4EMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |
| US-7312211-B2 | Pryanone compounds useful as reversible inhibitors of cysteine proteases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-12-25 | — | — | US | disclosed |