Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.71 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.71 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.71 |
| ▸ | MTOR | P42345 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | MLNR | O43193 | 2/20 | 0.71 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.71 |
| ▸ | CNR1 | P21554 | 1/20 | 0.71 |
| ▸ | HRH1 | P35367 | 1/20 | 0.71 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.71 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.71 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.57 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.55 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.55 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.55 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.55 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434762 | 0.98 | ADORA3 (0.68) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| SCHEMBL1434767 | 0.98 | ADORA3 (0.68) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| SCHEMBL336826 | 0.90 | ADORA3 (0.68) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| SCHEMBL5275957 | 0.84 | ADORA3 (0.90) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| SCHEMBL7590320 | 0.84 | ADORA3 (0.90) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| Lercanidipine SCHEMBL9957683 | 0.83 | ADORA3 (1.00) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| Lercanidipine SCHEMBL25268 | 0.83 | ADORA3 (1.00) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| Lercanidipine SCHEMBL8415026 | 0.83 | ADORA3 (1.00) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| Lercanidipine SCHEMBL29541187 | 0.83 | ADORA3 (1.00) | ADORA3ADRA1ASLC6A3MTORRAB9A | |
| Lercanidipine SCHEMBL25269 | 0.83 | ADORA3 (1.00) | ADORA3ADRA1ASLC6A3MTORRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101729-B1 | SELF-MICROEMULSIFYING DRUG DELIVERY SYSTEMS | LEK PHARMACEUTICALS (SI) | 2011-03-30 | — | — | EP | disclosed |
| EP-1961412-A1 | Self-microemulsifying drug delivery systems | LEK Pharmaceuticals D.D. (SI) | 2008-08-27 | — | — | EP | disclosed |