Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8350850 | 0.78 | PER2 (0.46) | PER2CYP2C19MEN1KMT2ATP53 | |
| SCHEMBL14347756 | 0.77 | PER2 (0.47) | PER2SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL12228962 | 0.76 | PER2 (0.48) | PER2PRMT5WDR77CRY2SMN1; SMN2 | |
| SCHEMBL13299412 | 0.76 | SMN1; SMN2 (0.49) | PTGS2SMN1; SMN2MEN1KMT2ATP53 | |
| SCHEMBL12221 | 0.75 | MEN1 (0.47) | CYP2D6SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL8350786 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2MEN1KMT2ATP53RAB9A | |
| SCHEMBL15973077 | 0.73 | PER2 (0.52) | PER2PRMT5WDR77CRY2SMN1; SMN2 | |
| SCHEMBL5737672 | 0.72 | POLB (0.47) | PER2SMN1; SMN2MEN1KMT2AMAPK1 | |
| SCHEMBL14347760 | 0.72 | SMN1; SMN2 (0.51) | CYP2D6SMN1; SMN2CYP2C19MEN1KMT2A | |
| SCHEMBL24635088 | 0.71 | KMT2A (0.49) | CYP2D6CYP2C19MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312214-B2 | 1, 1-disubstituted cycloalkyl derivatives as factor Xa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |