Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 7/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 7/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14348315 | 0.89 | CYP11B2 (0.40) | CYP11B2ARCCNCCDK8KDM1A | |
| SCHEMBL14347699 | 0.86 | CYP11B2 (0.41) | CYP11B2ARCCNCCDK8KDM1A | |
| SCHEMBL14347764 | 0.84 | CYP11B2 (0.39) | CYP11B2ARCCNCCDK8 | |
| SCHEMBL14347694 | 0.84 | CYP11B2 (0.38) | CYP11B2ARCCNCCDK8KDM1A | |
| SCHEMBL14348168 | 0.81 | CYP11B2 (0.37) | CYP11B2ARCCNCCDK8KDM1A | |
| SCHEMBL14347758 | 0.80 | CYP11B2 (0.43) | CYP11B2ARCCNCCDK8KDM1A | |
| SCHEMBL6469428 | 0.79 | AR (0.58) | CYP11B2ARCCNCCDK8CYP11B1 | |
| SCHEMBL14348169 | 0.78 | CYP11B2 (0.43) | CYP11B2ARCCNCCDK8KDM1A | |
| SCHEMBL14347763 | 0.78 | CYP11B2 (0.34) | CYP11B2ARCCNCCDK8KDM1A | |
| SCHEMBL14347623 | 0.74 | AR (0.42) | CYP11B2ARCCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007145349-A2 | SUBSTITUTED PYRROLE DERIVATIVES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-12-21 | — | — | WO | disclosed |