Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085048 | 0.89 | P2RX7 (0.48) | P2RX7 | |
| SCHEMBL4137642 | 0.88 | P2RX7 (0.61) | P2RX7 | |
| SCHEMBL14402966 | 0.86 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL14347720 | 0.86 | P2RX7 (0.57) | P2RX7 | |
| SCHEMBL14347206 | 0.84 | P2RX7 (0.53) | P2RX7 | |
| SCHEMBL14347641 | 0.84 | P2RX7 (0.60) | P2RX7 | |
| SCHEMBL14347721 | 0.83 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL14347205 | 0.83 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL14347576 | 0.83 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL14272604 | 0.81 | P2RX7 (0.55) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1862451-A1 | Adamantane derivatives for the treatment of inflammatory diseases | AstraZeneca AB (SE) | 2007-12-05 | — | — | EP | disclosed |