Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | LCAT | P04180 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18745857 | 0.76 | MAP3K12 (0.46) | — | |
| SCHEMBL18745797 | 0.76 | MAP3K12 (0.46) | — | |
| SCHEMBL26248564 | 0.75 | ACACB (0.37) | ACACBPANK3LCAT | |
| SCHEMBL8082710 | 0.71 | ACACB (0.38) | ACACBPANK3LCAT | |
| SCHEMBL21162008 | 0.70 | ACACB (0.47) | ACACBPANK3 | |
| SCHEMBL17693898 | 0.69 | SMPD3 (0.42) | ACACB | |
| SCHEMBL14349206 | 0.69 | SMPD3 (0.42) | ACACB | |
| SCHEMBL17693901 | 0.69 | SMPD3 (0.42) | ACACB | |
| SCHEMBL23023563 | 0.69 | ATR (0.43) | ACACB | |
| SCHEMBL11402871 | 0.67 | ACACB (0.50) | ACACBPANK3LCAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312209-B2 | Acridone inhibitors of IMPDH enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |
| US-7312209-B2 | Acridone inhibitors of IMPDH enzyme | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-25 | — | — | US | disclosed |