Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 8/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | MTOR | P42345 | 7/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 6/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 6/20 | 0.42 |
| ▸ | ATRIP | Q8WXE1 | 6/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 6/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 4/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 4/20 | 0.40 |
| ▸ | MAPKAP1 | Q9BPZ7 | 4/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 4/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082710 | 0.81 | ACACB (0.38) | ACACB | |
| SCHEMBL15142035 | 0.80 | ATR (0.46) | ATRPIK3CAPIK3CDMTORCHEK1 | |
| SCHEMBL15141830 | 0.80 | ATR (0.46) | ATRPIK3CAPIK3CDMTORCHEK1 | |
| SCHEMBL21588447 | 0.80 | AKR1C3 (0.46) | ATRPIK3CAPIK3CDMTORCHEK1 | |
| SCHEMBL15141832 | 0.80 | ATR (0.46) | ATRPIK3CAPIK3CDMTORCHEK1 | |
| SCHEMBL21588289 | 0.80 | AKR1C3 (0.46) | ATRPIK3CAPIK3CDMTORCHEK1 | |
| SCHEMBL21588307 | 0.80 | AKR1C3 (0.46) | ATRPIK3CAPIK3CDMTORCHEK1 | |
| SCHEMBL17693898 | 0.78 | SMPD3 (0.42) | ACACB | |
| SCHEMBL14349206 | 0.78 | SMPD3 (0.42) | ACACB | |
| SCHEMBL17693901 | 0.78 | SMPD3 (0.42) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | PFIZER INC. (US) | 2023-04-25 | — | — | US | disclosed |
| WO-2021032992-A1 | PHARMACEUTICAL COMPOUNDS | ReViral Limited (GB) | 2021-02-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11634425-B2 | Pharmaceutical compounds | GABRA6, CHRNA6, CNR1 | ATR 3033/4885PIK3CA 4834/4885PIK3CD 4789/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.