Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6578393 | 0.85 | NPC1 (0.57) | NPC1MAPTALDH1A1HRH3DRD2 | |
| SCHEMBL14352056 | 0.85 | NPC1 (0.57) | NPC1MAPTALDH1A1HRH3DRD2 | |
| SCHEMBL12285362 | 0.79 | NPC1 (0.50) | NPC1MAPTALDH1A1HRH3DRD2 | |
| SCHEMBL3051865 | 0.79 | NPC1 (0.54) | NPC1MAPTALDH1A1NOS1NOS2 | |
| SCHEMBL11482680 | 0.76 | MAOB (0.43) | NPC1NOS1NOS2 | |
| SCHEMBL20181058 | 0.76 | NOS2 (0.40) | NPC1MAPTNOS1NOS2RAB9A | |
| SCHEMBL10521892 | 0.76 | NPC1 (0.47) | NPC1MAPTALDH1A1HRH3DRD2 | |
| SCHEMBL14351756 | 0.75 | MAPT (0.72) | NPC1MAPTALDH1A1HRH3DRD2 | |
| SCHEMBL9417511 | 0.75 | GRM2 (0.39) | ALDH1A1NOS1NOS2TAAR1 | |
| SCHEMBL27866966 | 0.75 | NOS2 (0.41) | NPC1MAPTNOS1NOS2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481756-B2 | Curable composition | THREEBOND FINE CHEMICAL CO., LTD. (JP) | 2016-11-01 | — | — | US | disclosed |
| US-20130005854-A1 | CURABLE COMPOSITION | THREE BOND CO., LTD. (JP) | 2013-01-03 | — | — | US | disclosed |