Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | GLB1 | P16278 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | CTRC | Q99895 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14352338 | 1.00 | NPC1 (0.56) | NPC1MEN1KMT2AGLB1CTRB1 | |
| SCHEMBL14690091 | 0.90 | NOS3 (0.54) | NPC1MEN1KMT2AGLB1CTRB1 | |
| SCHEMBL14690090 | 0.90 | NOS3 (0.54) | NPC1MEN1KMT2AGLB1CTRB1 | |
| Parahydroxybenzyl Alcohol SCHEMBL62690 | 0.84 | — | — | |
| SCHEMBL11693103 | 0.83 | ESR1 (0.70) | NPC1MEN1KMT2AGLB1CTRB1 | |
| SCHEMBL11693113 | 0.83 | ESR1 (0.70) | NPC1MEN1KMT2AGLB1CTRB1 | |
| Parahydroxybenzyl Alcohol SCHEMBL10792062 | 0.82 | ESR1 (0.58) | NPC1MEN1KMT2AMAPTCA2 | |
| Parahydroxybenzyl Alcohol SCHEMBL27929616 | 0.82 | ESR1 (0.58) | NPC1MEN1KMT2AMAPTCA2 | |
| Parahydroxybenzyl Alcohol SCHEMBL27913908 | 0.82 | ESR1 (0.58) | NPC1MEN1KMT2AMAPTCA2 | |
| Parahydroxybenzyl Alcohol SCHEMBL27834691 | 0.82 | ESR1 (0.58) | NPC1MEN1KMT2AMAPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114752208-A | High-dielectric-constant polymer film material and preparation method thereof | 上海交通大学 | 2022-07-15 | — | — | CN | claimed |
| US-20240262949-A1 | TWO-WAY SHAPE MEMORY POLYURETHANE AND PREPARATION METHOD THEREOF | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2024-08-08 | — | — | US | disclosed |
| CN-116239753-B | Two-way shape memory polyurethane and preparation method thereof | 上海交通大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-116239753-A | Two-way shape memory polyurethane and preparation method thereof | 上海交通大学 | 2023-06-09 | — | — | CN | disclosed |
| CN-114752208-A | High-dielectric-constant polymer film material and preparation method thereof | 上海交通大学 | 2022-07-15 | — | — | CN | disclosed |
| US-9345781-B2 | Targeted dendrimer-drug conjugates | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-05-24 | — | — | US | disclosed |
| US-20130004427-A1 | TARGETED DENDRIMER-DRUG CONJUGATES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130004427-A1 | TARGETED DENDRIMER-DRUG CONJUGATES | FOLH1, DNPEP, PIGO | NPC1 1219/4885MEN1 3620/4885KMT2A 961/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.