SCHEMBL14355624

SCHEMBL14355624

COCCNc1c2ccc(NC(=O)CCN3CCCC3)cc2nc2cc(NC(=O)CCN3CCCC3)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 20/20 1.00
▸ POT1 Q9NUX5 3/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14355614 0.89 TERT (1.00) TERTPOT1
SCHEMBL14355590 0.86 TERT (1.00) TERTPOT1
SCHEMBL14355612 0.84 TERT (1.00) TERTPOT1
SCHEMBL14355659 0.84 TERT (0.81) TERTPOT1
SCHEMBL14355668 0.84 TERT (1.00) TERTPOT1
SCHEMBL14355607 0.83 TERT (1.00) TERTPOT1
SCHEMBL14355569 0.83 TERT (1.00) TERTPOT1
SCHEMBL13989200 0.83 TERT (1.00) TERTPOT1
SCHEMBL14355591 0.82 TERT (0.75) TERTPOT1
SCHEMBL13989205 0.82 TERT (1.00) TERTPOT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 — — US disclosed
US-7300930-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-11-27 — — US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 — — US disclosed
US-7160896-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2007-01-09 — — US disclosed
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