Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 11/20 | 0.61 |
| ▸ | BMP4 | P12644 | 4/20 | 0.60 |
| ▸ | FLT1 | P17948 | 2/20 | 0.60 |
| ▸ | FLT4 | P35916 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | BMPR1B | O00238 | 3/20 | 0.51 |
| ▸ | BMPR1A | P36894 | 3/20 | 0.51 |
| ▸ | ACVRL1 | P37023 | 3/20 | 0.51 |
| ▸ | ACVR1 | Q04771 | 3/20 | 0.51 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.51 |
| ▸ | BMPR2 | Q13873 | 1/20 | 0.51 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | ACVR2A | P27037 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30837690 | 0.86 | KDR (0.46) | KDRBMP4FLT1FLT4KMT2A | |
| SCHEMBL7112314 | 0.81 | KDR (0.59) | KDRBMP4FLT1FLT4KMT2A | |
| SCHEMBL29799087 | 0.80 | KDR (0.61) | KDRBMP4FLT1FLT4SMPD3 | |
| Hydrochloric Acid SCHEMBL29504907 | 0.78 | KDR (0.59) | KDRBMP4FLT1FLT4SMPD3 | |
| SCHEMBL7610618 | 0.76 | KDR (1.00) | KDRBMP4FLT1FLT4KMT2A | |
| SCHEMBL16177068 | 0.75 | IRAK4 (0.52) | BMP4SMPD3IRAK4 | |
| Hydrochloric Acid SCHEMBL30172429 | 0.75 | BMP4 (0.50) | KDRBMP4BMPR1BBMPR1AACVRL1 | |
| SCHEMBL9175179 | 0.75 | BMP4 (0.50) | KDRBMP4FLT1FLT4SMPD3 | |
| SCHEMBL2059685 | 0.75 | KDR (1.00) | KDRBMP4FLT1FLT4KMT2A | |
| SCHEMBL31227929 | 0.74 | PCSK9 (0.49) | BMP4SMPD3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147647-A1 | PYRAZOLOPYRIMIDINES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, METHODS OF PREPARING SAME AND USES OF SAME. | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-27 | — | — | WO | disclosed |