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Sugi Predict / Targets / BMP4

BMP4

Bone morphogenetic protein 4 · P12644 · BMP4 on Sugi Atlas →

2,551 patent compounds predicted against BMP4, 1,740 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2059665 SCHEMBL2059665 1.00 10/20
SCHEMBL11953447 SCHEMBL11953447 1.00 10/20
SCHEMBL12779929 SCHEMBL12779929 0.77 10/20
SCHEMBL12779932 SCHEMBL12779932 0.62 10/20
SCHEMBL12779924 SCHEMBL12779924 0.50 10/20
SCHEMBL11953443 SCHEMBL11953443 1.00 9/20
SCHEMBL11953449 SCHEMBL11953449 1.00 9/20
SCHEMBL14671947 SCHEMBL14671947 0.79 9/20
SCHEMBL14671967 SCHEMBL14671967 0.72 9/20
SCHEMBL2059669 SCHEMBL2059669 0.70 9/20
SCHEMBL2059674 SCHEMBL2059674 0.68 9/20
SCHEMBL11954474 SCHEMBL11954474 0.66 9/20
SCHEMBL2059691 SCHEMBL2059691 0.62 9/20
SCHEMBL12779933 SCHEMBL12779933 0.50 9/20
Dorsomorphin Dorsomorphin (SCHEMBL463155) 1.00 8/20
SCHEMBL2059672 SCHEMBL2059672 1.00 8/20
Dorsomorphin Dorsomorphin (SCHEMBL2119244) 0.98 8/20
SCHEMBL12844954 SCHEMBL12844954 0.80 8/20
SCHEMBL11953874 SCHEMBL11953874 0.69 8/20
SCHEMBL14656672 SCHEMBL14656672 0.54 8/20

Clinical trials — most relevant to BMP4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Vitamin D and Carboxy PTH Fragments in Coronary Calcification PHASE4WITHDRAWN
Socket Augmentation Using Atorvastatin With Or Without PRGF (Clinical and Histomorphometric Study) PHASE4COMPLETED
A Multi-center, Comparative Clinical Trial to Evaluate the Efficacy and Safety of Inject BMP in Patients Undergoing Transforaminal Lumbar Interbody Fusion PHASE3UNKNOWN
The Use of Adhesion Molecule Loaded Hydrogel With Minimally Invasive Surgical Technique in Treatment of Periodontal Intrabony Defect PHASE1/PHASE2COMPLETED
A Study to Evaluate the Safety and Efficacy of Vactosertib and Imatinib in Patients With Advanced Desmoid Tumor PHASE1/PHASE2COMPLETED
Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee PHASE2COMPLETED
Parallel Study Between BMP-2 and Autologous Bone Graft After Ilizarow Treatment PHASE1COMPLETED
Double-Blind, Randomized, Single Dose Escalation Safety Study of Intraarticular Bone Morphogenic Protein (38A BMP-7) in Subjects With Osteoarthritis (OA) of the Knee PHASE1COMPLETED
Short-term Impact of Cyplexinol® on Self-reported Joint Pain nanCOMPLETED
Comparison of Bone Morphogenetic Protein-4 (BMP-4) and 7 Levels Between Control and Polycystic Ovarian Syndrome (PCOS) Patients. nanUNKNOWN
Role of Novel Biomarkers Associated With In-stent Restenosis After Percutaneous Coronary Intervention nanUNKNOWN
Physiopathology of Pulmonary Arterial Hypertension: Mechanistic Studies nanUNKNOWN
The Role of TBX3 in Human ES Cell Differentiation nanWITHDRAWN
Therapeutic Irrigation Procedures to Treat Apical Periodontitis nanCOMPLETED
Immediate Implants in Maxillary Premolar Region Using Xenograft vs Allograft nanUNKNOWN
The Effect of Genetic Polymorphisms on the Success of Vital Pulp Therapy nanACTIVE_NOT_RECRUITING
Early Regenerative Intervention for Post-Traumatic Osteoarthritis nanUNKNOWN
Osteogenic Profiling of Normal Calvarial Bone nanCOMPLETED
Genetic and Environmental Characteristics of Primary Pulmonary Hypertension nanCOMPLETED
Induce XT™ Bone Graft in Foot and Ankle Fusion nanENROLLING_BY_INVITATION
Comparative Analysis of Gremlin-1, Syndecan-4 and IL-1 Beta Levels in Gingival Crevicular Fluid Among İndividuals With Periodontal Health and Stage III Periodontitis, Considering Both Smokers and Non-Smokers, Before and After Non-Surgical Periodontal Therapy nanACTIVE_NOT_RECRUITING
AO CSH Mainstream Study on Cervical Spine Degeneration nanNOT_YET_RECRUITING
Effect of BMPR-2 Gene Mutations on Hemodynamic Response by Iloprost Inhalation in Pulmonary Arterial Hypertension nanCOMPLETED
Evaluation of the Osteoinductivity of Atorvastatin Combined With β-TCP nanNOT_YET_RECRUITING
The OsteoStrand Plus Deformity Study nanUNKNOWN
Importance of Neurogenic Inflammation in the Angiogenic Response of the Dental Pulp as a Defensive Response nanCOMPLETED
Effect of Super-GDF9 on CAPA-IVM of COCs From Small Antral Follicles nanRECRUITING
Assessment of Guided Bone Regeneration in Atrophic Anterior Maxilla nanUNKNOWN
3Mixstatin ,Tri-Antibiotic Mix & Simvastatin in the Treatment of Primary Molars nanUNKNOWN
StratosPHere (Non-interventional Study) nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a BMP4 binder may also engage these)

ProteinNameSimilarity
Q06826 — 1.000 Q06826 →
Q2KJH1 — 1.000 Q2KJH1 →
Q29607 — 1.000 Q29607 →
O46576 — 1.000 O46576 →
P21274 — 1.000 P21274 →
Q90751 — 1.000 Q90751 →
O46564 — 1.000 O46564 →
P21275 — 1.000 P21275 →
Q90752 — 1.000 Q90752 →
P49001 — 1.000 P49001 →
P25703 — 1.000 P25703 →
Q8MJV5 — 1.000 Q8MJV5 →
BMP2 Bone morphogenetic protein 2 1.000 landscape →
O19006 — 1.000 O19006 →
P30884 — 0.998 P30884 →
Q804S2 — 0.998 Q804S2 →
P30885 — 0.997 P30885 →
Q4AEG6 — 0.995 Q4AEG6 →
Q9UK05 — 0.994 Q9UK05 →
Q9Z1W4 — 0.994 Q9Z1W4 →
P27091 — 0.993 P27091 →
P85857 — 0.993 P85857 →
O95393 — 0.993 O95393 →
O95390 — 0.992 O95390 →
P34822 — 0.992 P34822 →
Q9R229 — 0.992 Q9R229 →
Q07104 — 0.992 Q07104 →
Q9WV56 — 0.992 Q9WV56 →
F1QWZ4 — 0.991 F1QWZ4 →
Q9Z217 — 0.991 Q9Z217 →