Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TK2 | O00142 | 2/20 | 0.40 |
| ▸ | TK1 | P04183 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850332 | 0.84 | TYMP (0.48) | TYMPMAPK1HPGDTK2TK1 | |
| SCHEMBL2641394 | 0.79 | MAPK1 (0.51) | TYMPMAPK1HPGDTK2TK1 | |
| SCHEMBL16382269 | 0.79 | MAPK1 (0.51) | TYMPMAPK1HPGDTK2TK1 | |
| SCHEMBL8444953 | 0.78 | TYMP (0.50) | TYMPMAPK1HPGDTK2TK1 | |
| SCHEMBL6029061 | 0.78 | HPGD (0.53) | TYMPMAPK1HPGDTK2TK1 | |
| SCHEMBL13402919 | 0.78 | TYMP (0.54) | TYMPMAPK1HPGDTK2TK1 | |
| SCHEMBL4088248 | 0.78 | UPP1 (0.57) | TYMPMAPK1HPGD | |
| SCHEMBL6029548 | 0.78 | TYMP (0.50) | TYMPMAPK1HPGDTK2TK1 | |
| SCHEMBL7215304 | 0.78 | TYMP (0.50) | TYMPMAPK1HPGDTK2TK1 | |
| SCHEMBL7219926 | 0.76 | MAPK1 (0.54) | TYMPMAPK1HPGDTK2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291602-B2 | 11,12-lactone bicyclolides | ENANTA PHARMACEUTICALS, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-7291602-B2 | 11,12-lactone bicyclolides | ENANTA PHARMACEUTICALS, INC. (US) | 2007-11-06 | — | — | US | disclosed |