Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | PIR | O00625 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA2 | P00918 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 5/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.41 |
| ▸ | CA3 | P07451 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1774413 | 0.93 | CYP2C19 (0.65) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL2935232 | 0.93 | CYP2C19 (0.65) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL1774411 | 0.93 | CYP2C19 (0.65) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL13177791 | 0.87 | CYP2C19 (0.55) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL1775481 | 0.87 | CYP2C19 (0.77) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL1775480 | 0.87 | CYP2C19 (0.77) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL2937262 | 0.87 | CYP2C19 (0.77) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL2938712 | 0.83 | CYP2C19 (0.54) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL1774767 | 0.83 | CYP2C19 (0.54) | CYP2C19KMT2AMEN1F2PRSS1 | |
| SCHEMBL1774769 | 0.83 | CYP2C19 (0.54) | CYP2C19KMT2AMEN1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140957-A1 | SULFIMIDES AS PROTEIN KINASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-13 | — | — | WO | disclosed |