Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | PIR | O00625 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775480 | 1.00 | CYP2C19 (0.77) | CYP2C19KMT2AMEN1PIRACHE | |
| SCHEMBL1775481 | 1.00 | CYP2C19 (0.77) | CYP2C19KMT2AMEN1PIRACHE | |
| SCHEMBL1774413 | 0.94 | CYP2C19 (0.65) | CYP2C19KMT2AMEN1PIRACHE | |
| SCHEMBL1774411 | 0.94 | CYP2C19 (0.65) | CYP2C19KMT2AMEN1PIRACHE | |
| SCHEMBL2935232 | 0.94 | CYP2C19 (0.65) | CYP2C19KMT2AMEN1PIRACHE | |
| SCHEMBL17015173 | 0.87 | CYP2C19 (1.00) | CYP2C19KMT2AMEN1PIRSMN1; SMN2 | |
| SCHEMBL16317067 | 0.87 | CYP2C19 (1.00) | CYP2C19KMT2AMEN1PIRSMN1; SMN2 | |
| SCHEMBL14355817 | 0.87 | CYP2C19 (0.56) | CYP2C19KMT2AMEN1PIRACHE | |
| SCHEMBL2938712 | 0.85 | CYP2C19 (0.54) | CYP2C19KMT2AMEN1PIRALDH1A1 | |
| SCHEMBL1774767 | 0.85 | CYP2C19 (0.54) | CYP2C19KMT2AMEN1PIRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2029552-B1 | SULFIMIDES AS PROTEIN KINASE INHIBITORS | BAYER SCHERING PHARMA AG (DE) | 2010-09-22 | — | — | EP | disclosed |
| EP-2029552-A1 | SULFIMIDES AS PROTEIN KINASE INHIBITORS | Bayer Schering Pharma AG (DE) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007140957-A1 | SULFIMIDES AS PROTEIN KINASE INHIBITORS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-13 | — | — | WO | disclosed |