Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 13/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13391538 | 1.00 | ACKR3 (0.44) | ACKR3HRH3TBK1OGA | |
| SCHEMBL13391256 | 0.86 | CCR5 (0.38) | ACKR3TBK1 | |
| SCHEMBL13391517 | 0.85 | ACKR3 (0.42) | ACKR3TBK1 | |
| SCHEMBL14355995 | 0.83 | ACKR3 (0.40) | ACKR3TBK1 | |
| SCHEMBL13391321 | 0.83 | ACKR3 (0.40) | ACKR3TBK1 | |
| SCHEMBL13391263 | 0.83 | CYP3A4 (0.48) | — | |
| SCHEMBL13391261 | 0.81 | ACKR3 (0.42) | ACKR3TBK1 | |
| SCHEMBL13391111 | 0.81 | ACKR3 (0.42) | ACKR3TBK1 | |
| SCHEMBL13409692 | 0.81 | ACKR3 (0.42) | ACKR3TBK1 | |
| SCHEMBL13391222 | 0.81 | ACKR3 (0.42) | ACKR3TBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7300941-B2 | Non-imidazole compounds | SCHERING CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |
| US-7300941-B2 | Non-imidazole compounds | SCHERING CORPORATION (US) | 2007-11-27 | — | — | US | disclosed |