Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.39 |
| ▸ | PPARA | Q07869 | 5/20 | 0.39 |
| ▸ | PPARD | Q03181 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | WDR5 | P61964 | 2/20 | 0.36 |
| ▸ | BRS3 | P32247 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.36 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370610 | 0.99 | PPARG (0.39) | PPARGPPARAPPARDCYP2C9KMT2A | |
| SCHEMBL14356265 | 0.91 | CYP2C9 (0.41) | CYP2C9KMT2AMEN1ALDH1A1WDR5 | |
| Agn-201904 SCHEMBL5764653 | 0.90 | CYP2C9 (0.41) | PPARGPPARAPPARDCYP2C9KMT2A | |
| Agn-201904 SCHEMBL29596867 | 0.90 | CYP2C9 (0.41) | PPARGPPARAPPARDCYP2C9KMT2A | |
| Agn-201904 SCHEMBL2245875 | 0.90 | CYP2C9 (0.41) | PPARGPPARAPPARDCYP2C9KMT2A | |
| Agn-201904 SCHEMBL5330690 | 0.90 | CYP2C9 (0.41) | PPARGPPARAPPARDCYP2C9KMT2A | |
| SCHEMBL5763428 | 0.90 | PPARG (0.39) | PPARGPPARAPPARDCYP2C9KMT2A | |
| SCHEMBL7009476 | 0.90 | CYP2C9 (0.45) | CYP2C9KMT2AMEN1ALDH1A1WDR5 | |
| Agn-201904 SCHEMBL5764638 | 0.89 | CYP2C9 (0.40) | PPARGPPARAPPARDCYP2C9KMT2A | |
| SCHEMBL5763408 | 0.89 | PPARG (0.39) | PPARGPPARAPPARDCYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294716-B2 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALLERGAN, INC. (US) | 2007-11-13 | — | — | US | disclosed |
| US-7294716-B2 | Process for preparing isomerically pure prodrugs of proton pump inhibitors | ALLERGAN, INC. (US) | 2007-11-13 | — | — | US | disclosed |