SCHEMBL14356830

SCHEMBL14356830

C=Cc1ccc(CN(CC)CCO)cc1

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.44
ALDH1A1 P00352 5/20 0.41
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
CYP2C9 P11712 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 2/20 0.39
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
ALOX15 P16050 1/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL274543 0.90 HTT (0.42) HRH3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL20464231 0.90 HTT (0.46) ALDH1A1CYP1A2CYP2D6CYP2C19CYP2C9
SCHEMBL21132741 0.89 HTT (0.41) HRH3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL14732595 0.86 HRH3 (0.53) HRH3ALDH1A1
SCHEMBL13766098 0.86 MAPT (0.53) HRH3ALDH1A1CYP1A2CYP2D6CYP2C19
SCHEMBL94062 0.86 HRH3 (0.59) HRH3ALDH1A1HDAC8HDAC6
Boric Acid SCHEMBL28203315 0.85 HTT (0.40) HRH3ALDH1A1CYP1A2CYP2D6CYP2C19
Hydrochloric Acid SCHEMBL20586696 0.84 HRH3 (0.57) HRH3ALDH1A1HDAC8HDAC6
SCHEMBL14356831 0.81 TSHR (0.46) ALDH1A1CYP1A2CYP2D6CYP2C19CYP2C9
SCHEMBL21407969 0.81 MAPT (0.46) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297382-B2 Ink-jet recording material AGFA-GEVAERT (BE) 2007-11-20 US disclosed
US-7297382-B2 Ink-jet recording material AGFA-GEVAERT (BE) 2007-11-20 US disclosed
EP-1419897-B1 Ink jet recording material AGFA GEVAERT (BE) 2007-06-27 EP disclosed