SCHEMBL274543

SCHEMBL274543

C=Cc1ccc(CN(CCO)CCO)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.42
ALDH1A1 P00352 4/20 0.42
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
POLB P06746 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
KDM4E B2RXH2 2/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
HDAC3 O15379 3/20 0.38
HDAC1 Q13547 3/20 0.38
HDAC8 Q9BY41 3/20 0.38
HDAC6 Q9UBN7 3/20 0.38
HRH3 Q9Y5N1 1/20 0.38
HDAC4 P56524 2/20 0.38
HDAC7 Q8WUI4 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20464231 0.96 HTT (0.46) HTTALDH1A1CYP1A2CYP2D6CYP2C9
SCHEMBL14356830 0.90 HRH3 (0.44) HTTALDH1A1CYP1A2CYP2D6CYP2C9
SCHEMBL9989362 0.89 MAPT (0.40) HTTALDH1A1CYP1A2CYP2D6CYP2C9
SCHEMBL13766098 0.89 MAPT (0.53) HTTALDH1A1CYP1A2CYP2D6CYP2C9
SCHEMBL21132741 0.88 HTT (0.41) HTTALDH1A1CYP1A2CYP2D6CYP2C9
SCHEMBL20468064 0.85 ALDH1A1 (0.39) HTTALDH1A1MAPTHDAC3HDAC1
SCHEMBL6390256 0.84 ALDH1A1 (0.50) HTTALDH1A1POLBKDM4EMAPT
SCHEMBL18493213 0.83 ALDH1A1 (0.55) ALDH1A1POLBMAPTHDAC3HDAC8
SCHEMBL13888904 0.83 HTT (0.53) HTTALDH1A1CYP1A2CYP2D6CYP2C9
SCHEMBL610061 0.81 HRH3 (0.62) ALDH1A1CYP1A2CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117467060-A Preparation method of amino functionalized polymer and application of amino functionalized polymer in carbon dioxide capture 浙江理工大学嵊州创新研究院有限公司 2024-01-30 CN claimed
CN-113121735-B Preparation method of two-dimensional anion exchange polymer, prepared polymer and application thereof 安徽大学 2022-09-02 CN claimed
EP-4570844-A1 NOVEL POLYTHIOPHENE/POLYANION COMPLEXES AGFA-GEVAERT NV (BE) 2025-06-18 EP disclosed
CN-117467060-A Preparation method of amino functionalized polymer and application of amino functionalized polymer in carbon dioxide capture 浙江理工大学嵊州创新研究院有限公司 2024-01-30 CN disclosed
CN-117467060-A Preparation method of amino functionalized polymer and application of amino functionalized polymer in carbon dioxide capture 浙江理工大学嵊州创新研究院有限公司 2024-01-30 CN disclosed
CN-113121735-B Preparation method of two-dimensional anion exchange polymer, prepared polymer and application thereof 安徽大学 2022-09-02 CN disclosed
EP-1720065-B1 Photosensitive lithographic printing plate FUJIFILM CORP (JP) 2017-06-14 EP disclosed
US-9465142-B2 Near-infrared absorptive composition, near-infrared cut filter using near-infrared absorptive composition, method for manufacturing near-infrared cut filter, and camera module and method for manufacturing camera module FUJIFILM CORPORATION (JP) 2016-10-11 US disclosed
US-9465142-B2 Near-infrared absorptive composition, near-infrared cut filter using near-infrared absorptive composition, method for manufacturing near-infrared cut filter, and camera module and method for manufacturing camera module FUJIFILM CORPORATION (JP) 2016-10-11 US disclosed
EP-1564591-B1 Polymerizable composition FUJIFILM CORP (JP) 2016-08-03 EP disclosed
EP-2131239-B1 Processing liquid for lithographic printing plate development and method of producing lithographic printing plates FUJIFILM CORP (JP) 2016-03-23 EP disclosed
US-20090087790-A1 METHOD OF PRODUCING A NEGATIVE PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2009-04-02 US disclosed
EP-2042309-A2 Method of producing a negative planographic printing plate FUJIFILM Corporation (JP) 2009-04-01 EP disclosed
US-7374863-B2 Polyurethane binder, photoinitiator, and acrylic acid; for use as image recording layer of negative lithographic printing plate precursor; drawing with laser light FUJIFILM CORPORATION (JP) 2008-05-20 US disclosed
US-7374863-B2 Polyurethane binder, photoinitiator, and acrylic acid; for use as image recording layer of negative lithographic printing plate precursor; drawing with laser light FUJIFILM CORPORATION (JP) 2008-05-20 US disclosed
US-20080057437-A1 heat-decomposable cured polyurethane having an aromatic group is directly connected to a urethane bond; high sensitivity to easily form a pattern FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-20080057437-A1 heat-decomposable cured polyurethane having an aromatic group is directly connected to a urethane bond; high sensitivity to easily form a pattern FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-7297382-B2 Ink-jet recording material AGFA-GEVAERT (BE) 2007-11-20 US disclosed
US-7297382-B2 Ink-jet recording material AGFA-GEVAERT (BE) 2007-11-20 US disclosed
EP-1419897-B1 Ink jet recording material AGFA GEVAERT (BE) 2007-06-27 EP disclosed