Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20870315 | 0.83 | GRM5 (0.48) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL14476025 | 0.83 | GRM5 (0.48) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL22048899 | 0.77 | GRM5 (0.51) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL1825269 | 0.77 | GRM5 (0.43) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL852827 | 0.74 | GRM5 (0.51) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL382392 | 0.74 | GRM5 (0.51) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL14358515 | 0.71 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL14476027 | 0.70 | GRM5 (0.48) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL21382705 | 0.70 | GRM5 (0.62) | GRM5ALDH1A1GAAMAPTHSD17B10 | |
| SCHEMBL30947103 | 0.70 | GRM5 (0.62) | GRM5ALDH1A1GAAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2723737-A1 | BRIDGED BICYCLIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | Kyorin Pharmaceutical Co., Ltd. (JP) | 2014-04-30 | — | — | EP | disclosed |
| WO-2013003383-A1 | BRIDGED BICYCLIC COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2013-01-03 | — | — | WO | disclosed |