SCHEMBL30947103

SCHEMBL30947103

C#Cc1ccc2c(n1)OCCN2

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 1/20 0.62
ALDH1A1 P00352 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HSD17B10 Q99714 1/20 0.33
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21382705 1.00 GRM5 (0.62) GRM5ALDH1A1GAAMAPTHSD17B10
Formic Acid SCHEMBL30309196 0.76 GRM5 (0.54) GRM5
SCHEMBL382392 0.74 GRM5 (0.51) GRM5ALDH1A1GAAMAPTHSD17B10
SCHEMBL22048899 0.74 GRM5 (0.51) GRM5ALDH1A1GAAMAPTHSD17B10
SCHEMBL852827 0.74 GRM5 (0.51) GRM5ALDH1A1GAAMAPTHSD17B10
SCHEMBL14476027 0.70 GRM5 (0.48) GRM5ALDH1A1GAAMAPTHSD17B10
SCHEMBL20870315 0.70 GRM5 (0.48) GRM5ALDH1A1GAAMAPTHSD17B10
SCHEMBL14476025 0.70 GRM5 (0.48) GRM5ALDH1A1GAAMAPTHSD17B10
SCHEMBL14358239 0.70 GRM5 (0.48) GRM5ALDH1A1GAAMAPTHSD17B10
SCHEMBL18237835 0.70 GRM5 (0.48) GRM5ALDH1A1GAAMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118894816-A 3, 3-Difluoroallylamine or salt thereof and pharmaceutical composition comprising the same 柳韩洋行 2024-11-05 CN disclosed
CN-113330001-B 3, 3-Difluoroallylamine or salt thereof and pharmaceutical composition comprising the same 柳韩洋行 2024-07-02 CN disclosed