SCHEMBL14358641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14358638	1.00	CA1 (0.56)	CA1CA2NR3C2RELAAPP
	SCHEMBL10926948	0.89	CA1 (0.68)	CA1CA2NR3C2MAPTALDH1A1
	SCHEMBL14358816	0.87	KEAP1 (0.58)	CA1CA2NR3C2MAPTALDH1A1
	SCHEMBL14358814	0.87	KEAP1 (0.58)	CA1CA2NR3C2MAPTALDH1A1
	SCHEMBL14359437	0.86	HPGD (0.58)	CA1CA2RELAAPPPTGS1
	SCHEMBL14358646	0.82	CA1 (0.51)	CA1CA2RELAAPPPTGS1
	SCHEMBL14358644	0.82	CA1 (0.51)	CA1CA2RELAAPPPTGS1
	SCHEMBL15218448	0.80	KEAP1 (0.67)	CA1CA2NR3C2ALDH1A1LMNA
	SCHEMBL14358482	0.80	CA1 (0.49)	CA1CA2RELAAPPPTGS1
	SCHEMBL28812414	0.80	CA1 (0.49)	CA1CA2RELAAPPPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.