SCHEMBL14358697

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14358694	1.00	HDAC4 (0.49)	HDAC4SGK1BRPF1MAP2K4HRH3
	SCHEMBL12678579	0.90	HDAC4 (0.45)	HDAC4SGK1BRPF1MAP2K4HRH3
	SCHEMBL14358482	0.87	CA1 (0.49)	HDAC4PTGS1KMT2A
	SCHEMBL14358479	0.87	CA1 (0.49)	HDAC4PTGS1KMT2A
	SCHEMBL21933263	0.83	EPHX2 (0.52)	HDAC4
	SCHEMBL3980159	0.78	CA1 (0.53)	HDAC4SGK1BRPF1MAP2K4HRH3
	SCHEMBL28207342	0.78	HDAC4 (0.47)	HDAC4SGK1BRPF1MAP2K4HRH3
	SCHEMBL21590270	0.78	CA1 (0.53)	HDAC4SGK1BRPF1MAP2K4HRH3
	SCHEMBL3088517	0.78	SGK1 (0.51)	HDAC4SGK1BRPF1MAP2K4HRH3
	SCHEMBL14830078	0.78	MAP2K4 (0.56)	HDAC4SGK1BRPF1MAP2K4KIT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.