Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SGK1 | O00141 | 2/20 | 0.44 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.44 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3088517 | 0.80 | SGK1 (0.51) | HDAC4SGK1BRPF1MAP2K4HRH3 | |
| SCHEMBL257524 | 0.80 | CA1 (0.53) | HDAC4SGK1BRPF1MAP2K4HRH3 | |
| SCHEMBL14830078 | 0.80 | MAP2K4 (0.56) | HDAC4SGK1BRPF1MAP2K4KIT | |
| SCHEMBL21590270 | 0.80 | CA1 (0.53) | HDAC4SGK1BRPF1MAP2K4HRH3 | |
| SCHEMBL3980159 | 0.80 | CA1 (0.53) | HDAC4SGK1BRPF1MAP2K4HRH3 | |
| SCHEMBL6850398 | 0.79 | HDAC4 (0.56) | HDAC4SGK1BRPF1MAP2K4OPRM1 | |
| SCHEMBL14358697 | 0.78 | HDAC4 (0.49) | HDAC4SGK1BRPF1MAP2K4HRH3 | |
| Hydrochloric Acid SCHEMBL18953642 | 0.78 | SGK1 (0.50) | HDAC4SGK1BRPF1MAP2K4HRH3 | |
| SCHEMBL14358694 | 0.78 | HDAC4 (0.49) | HDAC4SGK1BRPF1MAP2K4HRH3 | |
| SCHEMBL31678785 | 0.76 | PTGS1 (0.53) | HDAC4SGK1BRPF1MAP2K4PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105764888-B | A kind of new 3 azabicyclos [3.1.0] hexame derivatives and its medical usage | 株式会社三和化学研究所 | 2018-04-06 | — | — | CN | disclosed |