Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.55 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14126258 | 0.84 | HPGD (0.48) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL136169 | 0.82 | FTO (0.56) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL16544 | 0.81 | FTO (0.55) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL29472215 | 0.81 | FTO (0.55) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL10486825 | 0.81 | FTO (0.54) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL4321320 | 0.81 | FTO (0.54) | FTOMAPTMEN1KMT2AHPGD | |
| Hydrochloric Acid SCHEMBL5440613 | 0.81 | FTO (0.54) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL9013831 | 0.81 | FTO (0.54) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL6662140 | 0.80 | FTO (0.74) | FTOMAPTMEN1KMT2AHPGD | |
| SCHEMBL3189664 | 0.80 | FTO (0.66) | FTOMAPTMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10119972-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2018-11-06 | — | — | US | disclosed |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2018-01-11 | — | — | US | disclosed |
| US-9759726-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-09-12 | — | — | US | disclosed |
| EP-3129767-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | Academia Sinica (TW) | 2017-02-15 | — | — | EP | disclosed |
| CN-106415244-A | Reactive marker compounds and uses thereof | 中央研究院 | 2017-02-15 | — | — | CN | disclosed |
| WO-2015148915-A9 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2016-12-22 | — | — | WO | disclosed |
| US-20150309041-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-10-29 | — | — | US | disclosed |
| WO-2015148915-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-10-01 | — | — | WO | disclosed |
| WO-2013144656-A1 | ACTIVE SITE PROBES | ISIS INNOVATION LIMITED (GB) | 2013-10-03 | — | — | WO | disclosed |
| WO-2013001451-A1 | VECTOR FOR THE RELEASE OF AN ACTIVE AGENT WHICH IS PHOTOCLEAVABLE BY IRRADIATION IN THE VISIBLE | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2013-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150309041-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | MPI, AADAC, PAICS | FTO 2514/4885MAPT 4444/4885MEN1 2425/4885 |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | MPI, AADAC, PAICS | FTO 2389/4885MAPT 4417/4885MEN1 2466/4885 |
| US-10119972-B2 | Reactive labelling compounds and uses thereof | MPI, AADAC, PAICS | FTO 2389/4885MAPT 4417/4885MEN1 2466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.