Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CFD | P00746 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14360352 | 1.00 | LMNA (0.56) | LMNAPOLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1274636 | 0.84 | LMNA (0.54) | LMNAPOLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL1274635 | 0.84 | LMNA (0.54) | LMNAPOLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29360345 | 0.80 | TSHR (0.42) | LMNATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL19176162 | 0.80 | TSHR (0.42) | LMNATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL18112863 | 0.80 | TSHR (0.42) | LMNATAS1R3TAS1R1TAS1R2MEN1 | |
| SCHEMBL14837508 | 0.75 | ELANE (0.35) | LMNAMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14359836 | 0.75 | LMNA (0.65) | LMNAPOLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL14359838 | 0.75 | LMNA (0.65) | LMNAPOLBTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL31634863 | 0.74 | GAA (0.39) | LMNAMEN1KMT2AHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114133382-A | Microbicidal heterocycles | 先正达参股股份有限公司 | 2022-03-04 | — | — | CN | disclosed |
| US-9301530-B2 | Microbiocidal heterocycles | SYNGENTA PARTICIPATIONS AG (CH) | 2016-04-05 | — | — | US | disclosed |
| US-20140128406-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-05-08 | — | — | US | disclosed |
| EP-2726474-A1 | MICROBIOCIDAL HETEROCYCLES | Syngenta Participations AG (CH) | 2014-05-07 | — | — | EP | disclosed |
| WO-2013000943-A1 | MICROBIOCIDAL HETEROCYCLES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140128406-A1 | MICROBIOCIDAL HETEROCYCLES | CBR1, CBR3, NOX1 | LMNA 3301/4885POLB 3612/4885TAS1R3 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.