Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802677 | 0.79 | MAPT (0.41) | NPC1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL11912104 | 0.79 | MAPT (0.41) | NPC1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL13082776 | 0.73 | MME (0.31) | MMEPIK3CD | |
| SCHEMBL9891112 | 0.73 | NPC1 (0.35) | NPC1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL2931296 | 0.72 | MME (0.43) | MAPTMMEPIK3CD | |
| SCHEMBL15040816 | 0.72 | MME (0.43) | MAPTMMEPIK3CD | |
| SCHEMBL13558663 | 0.72 | MAPT (0.34) | NPC1ALDH1A1GAAMAPTRAB9A | |
| SCHEMBL13544349 | 0.72 | KMT2A (0.45) | GAAMAPTSMN1; SMN2MME | |
| SCHEMBL13178384 | 0.72 | MME (0.43) | MAPTMMEPIK3CD | |
| SCHEMBL16202441 | 0.72 | MME (0.36) | MAPTMMEPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021058027-A1 | PYRROLO HETEROARYL DERIVATIVE OR CONJUGATE THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 江苏恒瑞医药股份有限公司 | 2021-04-01 | — | — | WO | disclosed |
| EP-0867190-B1 | CYTOTOXIN COMPLEXES COMPRISING DIPEPTIDES | KYOWA HAKKO KOGYO KK (JP) | 2007-12-26 | — | — | EP | disclosed |