Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GPR3 | P46089 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | HTR5A | P47898 | 2/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363775 | 0.84 | SLC6A4 (0.41) | SLC6A4MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL14363778 | 0.84 | SLC6A4 (0.39) | SLC6A4MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL14363768 | 0.81 | SLC6A4 (0.48) | SLC6A4MEN1KMT2AMAOAKDM4E | |
| SCHEMBL14363769 | 0.78 | SMPD1 (0.41) | SLC6A4MEN1KMT2ACYP1A2MAPK1 | |
| SCHEMBL13877240 | 0.73 | SLC6A4 (0.46) | SLC6A4MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL3858428 | 0.71 | MCHR1 (0.52) | SLC6A4CYP1A2CYP2D6ADRA1ATSHR | |
| SCHEMBL14364159 | 0.71 | CHRNA7 (0.55) | SLC6A4MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL3857346 | 0.70 | MCHR1 (0.52) | SLC6A4CYP1A2CYP2D6ADRA1ATSHR | |
| SCHEMBL13877239 | 0.69 | SLC6A4 (0.43) | SLC6A4MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL14627593 | 0.69 | SLC6A4 (0.48) | SLC6A4CYP1A2CYP2D6HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147819-A1 | 3H,11H-OXAZOLO[3',4':1,2]PYRIDO[3,4-B]INDOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | FOURTILLAN (FR) | 2007-12-27 | — | — | WO | disclosed |