Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.52 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 2/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363779 | 0.84 | KIF11 (0.46) | MEN1KMT2A | |
| SCHEMBL14364171 | 0.84 | CHRNA7 (0.49) | CHRNA7ADRA1AADRA1DADRA1BPOLB | |
| SCHEMBL14364157 | 0.84 | CHRNA7 (0.49) | CHRNA7ADRA1AADRA1DADRA1BPOLB | |
| SCHEMBL14364155 | 0.82 | ADRA1D (0.50) | CHRNA7ADRA1AADRA1DADRA1BPOLB | |
| SCHEMBL14363770 | 0.81 | MAPT (0.54) | ADRA1AADRA1DCYP2D6CYP1A2HSD17B10 | |
| SCHEMBL14363773 | 0.78 | ABCG2 (0.52) | ADRA1ALMNAPDE5AMEN1KMT2A | |
| SCHEMBL3867321 | 0.76 | CHRNA7 (0.58) | CHRNA7ADRA1AADRA1DADRA1BPOLB | |
| SCHEMBL21648535 | 0.73 | CHRNA7 (0.42) | CHRNA7ADRA1AADRA1DADRA1BPOLB | |
| SCHEMBL21648518 | 0.73 | CHRNA7 (0.42) | CHRNA7ADRA1AADRA1DADRA1BPOLB | |
| SCHEMBL21648536 | 0.73 | CHRNA7 (0.42) | CHRNA7ADRA1AADRA1DADRA1BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147819-A1 | 3H,11H-OXAZOLO[3',4':1,2]PYRIDO[3,4-B]INDOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | FOURTILLAN (FR) | 2007-12-27 | — | — | WO | disclosed |