Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CPS1 | P31327 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345161 | 0.94 | F10 (0.48) | F10KCNH2F2CPS1CYP1A2 | |
| SCHEMBL5532103 | 0.94 | F10 (0.48) | F10KCNH2F2CPS1CYP1A2 | |
| SCHEMBL14345426 | 0.94 | F10 (0.45) | F10KCNH2TSHR | |
| SCHEMBL14345290 | 0.93 | KCNH2 (0.52) | F10KCNH2 | |
| SCHEMBL5531643 | 0.93 | F10 (0.47) | F10KCNH2F2CPS1CYP1A2 | |
| SCHEMBL14345283 | 0.91 | F10 (0.53) | F10KCNH2F2TSHR | |
| SCHEMBL5532168 | 0.91 | F10 (0.50) | F10KCNH2F2 | |
| SCHEMBL14366554 | 0.86 | KCNH2 (0.52) | F10KCNH2 | |
| SCHEMBL5534302 | 0.85 | F10 (0.53) | F10KCNH2F2GAA | |
| SCHEMBL5528854 | 0.85 | F10 (0.48) | F10KCNH2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |