Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345296 | 0.94 | KCNH2 (0.61) | KCNH2LMNAITGB3ITGA2BKMT2A | |
| SCHEMBL14345290 | 0.93 | KCNH2 (0.52) | KCNH2LMNAITGB3ITGA2BKMT2A | |
| SCHEMBL14345426 | 0.92 | F10 (0.45) | KCNH2ITGB3ITGA2BKMT2AF10 | |
| SCHEMBL14345441 | 0.90 | F10 (0.44) | KCNH2ITGB3ITGA2BKMT2AF10 | |
| SCHEMBL5528854 | 0.88 | F10 (0.48) | KCNH2ITGB3ITGA2BF10NPC1 | |
| SCHEMBL14345340 | 0.86 | KCNH2 (0.73) | KCNH2F10 | |
| SCHEMBL14366121 | 0.86 | F10 (0.49) | KCNH2F10 | |
| SCHEMBL14345133 | 0.85 | KCNH2 (0.72) | KCNH2LMNAF10 | |
| SCHEMBL14345258 | 0.85 | F10 (0.48) | KCNH2ITGB3ITGA2BF10NPC1 | |
| SCHEMBL14345123 | 0.85 | KCNH2 (0.58) | KCNH2LMNAKMT2AF10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |