Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 1.00 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.64 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.64 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 2/20 | 0.60 |
| ▸ | CNR2 | P34972 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.60 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12758274 | 0.93 | ESR1 (1.00) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL13038504 | 0.93 | ESR1 (1.00) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL25977046 | 0.92 | ESR1 (0.85) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL13176459 | 0.89 | ESR1 (0.81) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL25977050 | 0.86 | ESR1 (0.86) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL25977049 | 0.86 | ESR1 (0.86) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL9513638 | 0.85 | ESR1 (0.76) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| Butyl Gallate SCHEMBL35913 | 0.84 | ESR1 (1.00) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL28629629 | 0.84 | ESR1 (0.72) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL869061 | 0.83 | ESR1 (0.71) | ESR1LMNACYP1A2CYP2C19NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309615-B2 | High quantum yield acridinium compounds and their uses in improving assay sensitivity | SIEMENS MEDICAL SOLUTIONS DIAGNOSTIC (US) | 2007-12-18 | — | — | US | disclosed |