SCHEMBL28629629

SCHEMBL28629629

CCCCOC(=O)c1cc(C(=O)OCC)cc(C(=O)OCC)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.72
CYP1A2 P05177 3/20 0.61
CYP2C19 P33261 3/20 0.61
TSHR P16473 3/20 0.61
LMNA P02545 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
CYP2D6 P10635 1/20 0.61
MAPK1 P28482 1/20 0.61
NR1H2 P55055 1/20 0.61
RNASEL Q05823 1/20 0.61
CNR1 P21554 2/20 0.60
CNR2 P34972 2/20 0.60
AKR1C4 P17516 1/20 0.60
AKR1C3 P42330 1/20 0.60
AKR1C2 P52895 1/20 0.60
AKR1C1 Q04828 1/20 0.60
CYP2C9 P11712 2/20 0.59
CYP3A4 P08684 1/20 0.59
PDE4D Q08499 1/20 0.59
CA12 O43570 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9513638 0.94 ESR1 (0.76) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL5168199 0.90 CYP1A2 (0.70) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL5164901 0.89 ESR1 (0.77) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL16325360 0.88 CA12 (0.68) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL22289821 0.88 ESR1 (0.74) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL23250562 0.87 ESR1 (0.67) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL7592525 0.87 ESR1 (0.73) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL27893069 0.87 ESR1 (0.67) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL3404899 0.87 ESR1 (0.72) ESR1CYP1A2CYP2C19TSHRLMNA
SCHEMBL20250739 0.87 CNR1 (0.72) ESR1CYP1A2CYP2C19TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113412286-A Process for preparing polydienes having reduced cold flow properties 普利司通美国轮胎运营有限责任公司 2021-09-17 CN claimed
CN-113412286-A Process for preparing polydienes having reduced cold flow properties 普利司通美国轮胎运营有限责任公司 2021-09-17 CN disclosed