Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.44 |
| ▸ | PPARG | P37231 | 13/20 | 0.44 |
| ▸ | PPARD | Q03181 | 12/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366161 | 0.85 | PPARA (0.49) | PPARAPPARGPPARDNPC1RAB9A | |
| SCHEMBL14366196 | 0.82 | MAPT (0.47) | PPARAPPARGPPARDNPC1RAB9A | |
| SCHEMBL14366164 | 0.81 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL5274279 | 0.80 | PPARG (0.49) | PPARAPPARGPPARD | |
| SCHEMBL14366163 | 0.80 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5579706 | 0.78 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL14366174 | 0.78 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL6544277 | 0.78 | PPARA (0.51) | PPARAPPARGPPARDNPC1RAB9A | |
| SCHEMBL14366183 | 0.78 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL6543018 | 0.78 | PPARA (0.49) | PPARAPPARGPPARDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301033-B2 | PPAR-activating compound | KOWA CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |
| US-7301033-B2 | PPAR-activating compound | KOWA CO., LTD. (JP) | 2007-11-27 | — | — | US | disclosed |