Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.51 |
| ▸ | PPARG | P37231 | 15/20 | 0.51 |
| ▸ | PPARD | Q03181 | 14/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543018 | 0.92 | PPARA (0.49) | PPARAPPARGPPARDNPC1LMNA | |
| SCHEMBL6543006 | 0.86 | PPARA (0.56) | PPARAPPARGPPARD | |
| SCHEMBL6543072 | 0.86 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL6543464 | 0.86 | PPARA (0.48) | PPARAPPARGPPARDNPC1LMNA | |
| SCHEMBL6543071 | 0.84 | PPARA (0.65) | PPARAPPARGPPARD | |
| SCHEMBL6543916 | 0.84 | PPARA (0.63) | PPARAPPARGPPARD | |
| SCHEMBL6544084 | 0.84 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL2440051 | 0.83 | PPARA (0.58) | PPARAPPARGPPARDNPC1LMNA | |
| SCHEMBL6544117 | 0.83 | PPARA (0.57) | PPARAPPARGPPARD | |
| SCHEMBL2469118 | 0.83 | PPARG (0.71) | PPARAPPARGPPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |
| US-6653334-B1 | Electively activate peroxisome proliferator activated receptors | KOWA CO., LTD. (JP) | 2003-11-25 | — | — | US | disclosed |