SCHEMBL14366167

SCHEMBL14366167

O=C(O)c1cccc(OCCCN(Cc2ccc(Cl)cc2)c2nc3ccccc3o2)c1

nearest known ligand 0.66

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 20/20 0.66
PPARD Q03181 18/20 0.61
PPARG P37231 15/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14384237 0.98 PPARA (0.64) PPARAPPARDPPARG
SCHEMBL14366160 0.90 PPARA (0.60) PPARAPPARDPPARG
SCHEMBL14366176 0.90 PPARA (0.61) PPARAPPARDPPARG
SCHEMBL14366185 0.89 PPARA (0.58) PPARAPPARDPPARG
SCHEMBL14366180 0.88 PPARA (0.58) PPARAPPARDPPARG
SCHEMBL14366159 0.88 PPARA (0.68) PPARAPPARDPPARG
SCHEMBL5273391 0.87 PPARA (0.62) PPARAPPARDPPARG
SCHEMBL14366181 0.87 PPARA (0.67) PPARAPPARDPPARG
SCHEMBL14366169 0.85 PPARA (0.65) PPARAPPARDPPARG
SCHEMBL5275529 0.85 PPARA (0.59) PPARAPPARDPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7301033-B2 PPAR-activating compound KOWA CO., LTD. (JP) 2007-11-27 US disclosed
US-7301033-B2 PPAR-activating compound KOWA CO., LTD. (JP) 2007-11-27 US disclosed