SCHEMBL14366185

SCHEMBL14366185

O=C(O)c1ccc(OCCCCN(Cc2ccc(Cl)cc2)c2nc3ccccc3o2)cc1

nearest known ligand 0.58

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 19/20 0.58
PPARG P37231 16/20 0.56
PPARD Q03181 15/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14366176 0.97 PPARA (0.61) PPARAPPARGPPARD
SCHEMBL14366186 0.92 PPARG (0.54) PPARAPPARGPPARD
SCHEMBL14384237 0.91 PPARA (0.64) PPARAPPARGPPARD
SCHEMBL14366167 0.89 PPARA (0.66) PPARAPPARGPPARD
SCHEMBL14366177 0.89 PPARA (0.55) PPARAPPARGPPARD
SCHEMBL5272841 0.86 PPARA (0.58) PPARAPPARGPPARD
SCHEMBL14366189 0.86 PPARA (0.61) PPARAPPARGPPARD
SCHEMBL14366182 0.85 PPARA (0.51) PPARAPPARGPPARD
SCHEMBL14583428 0.85 PPARA (0.75) PPARAPPARGPPARD
SCHEMBL14366188 0.85 PPARA (0.62) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7301033-B2 PPAR-activating compound KOWA CO., LTD. (JP) 2007-11-27 US disclosed
US-7301033-B2 PPAR-activating compound KOWA CO., LTD. (JP) 2007-11-27 US disclosed
EP-1857447-A1 PPAR-ACTIVATING COMPOUND Kowa Company, Ltd. (JP) 2007-11-21 EP disclosed