Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.42 |
| ▸ | PPARG | P37231 | 15/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383238 | 0.90 | PPARG (0.42) | PPARAPPARGACACBPOLBPPARD | |
| SCHEMBL5379589 | 0.85 | PPARG (0.54) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL14366349 | 0.85 | PPARG (0.54) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL6150658 | 0.85 | PPARA (0.45) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL5428548 | 0.82 | PPARA (0.36) | PPARAPPARGLMNAL3MBTL1ACACB | |
| SCHEMBL14366347 | 0.82 | PPARA (0.36) | PPARAPPARGLMNAL3MBTL1ACACB | |
| SCHEMBL6151399 | 0.80 | PPARA (0.39) | PPARAPPARGLMNAL3MBTL1ACACB | |
| SCHEMBL14366363 | 0.78 | PPARG (0.56) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL5360147 | 0.76 | ESR1 (0.51) | PPARA | |
| SCHEMBL3694538 | 0.76 | ESR1 (0.51) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | PPARA 3/4885PPARG 1/4885LMNA 4004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.