Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 14/20 | 0.39 |
| ▸ | PPARG | P37231 | 13/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150601 | 0.91 | PPARA (0.45) | PPARAPPARGMMP1LMNAL3MBTL1 | |
| SCHEMBL6150658 | 0.84 | PPARA (0.45) | PPARAPPARGLMNAL3MBTL1PPARD | |
| SCHEMBL5363966 | 0.82 | PTPN1 (0.45) | PPARAPPARGL3MBTL1PPARDKMT2A | |
| SCHEMBL14366348 | 0.80 | PPARA (0.42) | PPARAPPARGLMNAL3MBTL1ACACB | |
| SCHEMBL6151412 | 0.79 | CACNA1B (0.39) | PPARAPPARG | |
| SCHEMBL6150912 | 0.79 | CACNA1B (0.39) | PPARAPPARG | |
| SCHEMBL5352421 | 0.78 | PPARA (0.48) | PPARAPPARGPPARD | |
| SCHEMBL5428548 | 0.77 | PPARA (0.36) | PPARAPPARGLMNAL3MBTL1ACACB | |
| SCHEMBL14366347 | 0.77 | PPARA (0.36) | PPARAPPARGLMNAL3MBTL1ACACB | |
| SCHEMBL5379589 | 0.76 | PPARG (0.54) | PPARAPPARGLMNAL3MBTL1PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |