Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 15/20 | 0.56 |
| ▸ | PPARD | Q03181 | 12/20 | 0.56 |
| ▸ | PPARA | Q07869 | 11/20 | 0.56 |
| ▸ | ACACB | O00763 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14366413 | 0.93 | PPARG (0.58) | PPARGPPARDPPARAACACBLTA4H | |
| SCHEMBL14392322 | 0.90 | PPARG (0.58) | PPARGPPARDPPARAACACB | |
| SCHEMBL5380492 | 0.89 | PPARA (0.54) | PPARGPPARDPPARA | |
| SCHEMBL5389701 | 0.87 | PPARA (0.73) | PPARGPPARDPPARA | |
| SCHEMBL5451332 | 0.87 | PPARA (0.73) | PPARGPPARDPPARA | |
| SCHEMBL6574076 | 0.85 | PPARA (0.53) | PPARGPPARDPPARA | |
| SCHEMBL5382224 | 0.85 | PPARA (0.53) | PPARGPPARDPPARA | |
| SCHEMBL14285167 | 0.84 | ACACB (0.53) | PPARGPPARDPPARAACACB | |
| SCHEMBL14285179 | 0.84 | ACACB (0.53) | PPARGPPARDPPARAACACB | |
| SCHEMBL14366512 | 0.83 | PPARA (0.71) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | BROOKS DAWN A | 2007-11-29 | — | — | US | disclosed |
| US-7192982-B2 | Modulators of peroxisome proliferator activated receptors | LIGAND PHARMACEUTICALS, INC. (US) | 2007-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276138-A1 | Modulators of peroxisome proliferator activated receptors | PPARG, NCOA4, PPARA | PPARG 1/4885PPARD 4/4885PPARA 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.