Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 12/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 5/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARD | Q03181 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14285179 | 1.00 | ACACB (0.53) | ACACBGAARAB9APPARAPPARG | |
| SCHEMBL14392322 | 0.88 | PPARG (0.58) | ACACBPPARAPPARGPPARD | |
| SCHEMBL6653115 | 0.87 | ACACB (0.52) | ACACBGAARAB9APPARA | |
| SCHEMBL6653118 | 0.87 | ACACB (0.52) | ACACBGAARAB9APPARA | |
| SCHEMBL4455242 | 0.85 | LDHA (0.59) | ACACBPPARAPPARGPPARD | |
| SCHEMBL5547976 | 0.85 | PTPN1 (0.57) | ACACBRAB9A | |
| SCHEMBL14285181 | 0.85 | PTPN1 (0.57) | ACACBRAB9A | |
| SCHEMBL5023087 | 0.85 | PTPN1 (0.57) | ACACBRAB9A | |
| SCHEMBL5023091 | 0.85 | OXTR (0.49) | ACACBGAARAB9APPARAPPARG | |
| SCHEMBL14285180 | 0.85 | PPARA (0.51) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7321056-B2 | Selective peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY (US) | 2008-01-22 | — | — | US | disclosed |
| US-20070066683-A1 | Selective peroxisome proliferator activated receptor modulators | ELI LILLY AND COMPANY | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066683-A1 | Selective peroxisome proliferator activated receptor modulators | PPARG, PPARD, PPARA | ACACB 97/4885GAA 1002/4885RAB9A 3614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.