Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14345283 | 0.93 | F10 (0.53) | F10KCNH2TSHR | |
| SCHEMBL14345442 | 0.91 | F10 (0.54) | F10KCNH2ALDH1A1KDM4EMAPT | |
| SCHEMBL14345426 | 0.91 | F10 (0.45) | F10KCNH2TSHRALDH1A1KDM4E | |
| SCHEMBL5533862 | 0.90 | F10 (0.58) | F10KCNH2ALDH1A1KDM4EMAPT | |
| SCHEMBL14345338 | 0.87 | F10 (0.56) | F10KCNH2ALDH1A1KDM4EMAPT | |
| SCHEMBL5534302 | 0.86 | F10 (0.53) | F10KCNH2 | |
| SCHEMBL14345123 | 0.86 | KCNH2 (0.58) | F10KCNH2ALDH1A1MAPTLMNA | |
| SCHEMBL5530868 | 0.86 | F10 (0.56) | F10KCNH2ALDH1A1KDM4EMAPT | |
| SCHEMBL5532251 | 0.85 | L3MBTL1 (0.51) | F10KCNH2ALDH1A1KDM4EMAPT | |
| SCHEMBL14345133 | 0.85 | KCNH2 (0.72) | F10KCNH2TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7312235-B2 | Benzamide inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2007-12-25 | — | — | US | disclosed |