SCHEMBL1436657

SCHEMBL1436657

NC(=O)c1ccc(CCO)c([N+](=O)[O-])c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 2/20 0.39
TSHR P16473 3/20 0.37
POLB P06746 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP3A4 P08684 3/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
MITF O75030 1/20 0.34
HTT P42858 1/20 0.33
ALOX15 P16050 1/20 0.33
PKM P14618 1/20 0.33
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL354095 0.84 TSHR (0.43) ALDH1A1KMT2ALMNATSHRPOLB
SCHEMBL29377050 0.83 TSHR (0.40) ALDH1A1TSHRPOLBL3MBTL1SMN1; SMN2
SCHEMBL872694 0.83 TSHR (0.40) ALDH1A1TSHRPOLBL3MBTL1SMN1; SMN2
SCHEMBL5710258 0.81 TSHR (0.44) ALDH1A1KMT2ALMNATSHRPOLB
SCHEMBL4456705 0.78 ALDH1A1 (0.39) ALDH1A1LMNATSHRPOLBTDP1
SCHEMBL27881224 0.78 TSHR (0.39) ALDH1A1KMT2ATSHRPOLBCYP3A4
SCHEMBL1437068 0.78 TSHR (0.39) ALDH1A1LMNATSHRPOLBTDP1
SCHEMBL8070789 0.76 ALDH1A1 (0.51) ALDH1A1KMT2ALMNATSHRPOLB
SCHEMBL22833863 0.75 TSHR (0.42) ALDH1A1KMT2ATSHRPOLBTDP1
SCHEMBL3949941 0.75 ALDH1A1 (0.36) ALDH1A1LMNATSHRPOLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1903161-A Composition for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer OREAL (FR) 2007-01-31 CN claimed
CN-1899244-A Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid OREAL (FR) 2007-01-24 CN claimed
CN-109310607-A The compound for carrying the azomethine type of quinoline derivatives unit is used for the purposes of dyeing keratin fibres 莱雅公司 2019-02-05 CN disclosed
CN-102018636-B Usage of drying oil for wash-protecting the color of artificially dyed keratin fibers OREAL 2012-12-26 CN disclosed
EP-2470155-A1 COSMETIC COMPOSITION FOR KERATIN FIBERS L'Oréal (FR) 2012-07-04 EP disclosed
CN-102481235-A Cosmetic composition for keratin fibers OREAL 2012-05-30 CN disclosed
CN-102018636-A Usage of drying oil for wash-protecting the color of artificially dyed keratin fibers OREAL 2011-04-20 CN disclosed
WO-2011024300-A1 COSMETIC COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2011-03-03 WO disclosed
EP-2201070-A2 AZO QUINOLINIUM COMPOUNDS COMPRISING A DISULPHIDE/THIOL UNIT, COMPOSITIONS CONTAINING SAME, PROCESS FOR DYEING KERATIN FIBRES AND DEVICE L'Oreal (FR) 2010-06-30 EP disclosed
EP-2170260-A1 AZO DERIVATIVES CONTAINING A PYRAZOLINONE UNIT FOR DYEING KERATIN FIBRES L'Oreal (FR) 2010-04-07 EP disclosed
WO-2009034059-A2 AZO QUINOLINIUM COMPOUNDS COMPRISING A DISULPHIDE/THIOL UNIT, COMPOSITIONS CONTAINING SAME, PROCESS FOR DYEING KERATIN FIBRES AND DEVICE L'OREAL (FR) 2009-03-19 WO disclosed
EP-1819682-A1 SYMMETRICAL CATIONIC TETRAAZO COMPOUNDS, FOR DYEING KERATIN FIBRES L'Oréal (FR) 2007-08-22 EP disclosed
WO-2007080183-A1 USE FOR THE DYEING WITH LIGHTENING EFFECT OF KERATIN SUBSTANCES OF A COMPOSITION COMPRISING A FLUORESCENT CYANINE DYE L'ORÉAL (FR) 2007-07-19 WO disclosed
CN-1903161-A Composition for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an asociative polymer OREAL (FR) 2007-01-31 CN disclosed
CN-1899244-A Agent for simultaneously bleaching and coloring of keratin fibres comprising an anionic or non-ionic dye and an inert organic liquid OREAL (FR) 2007-01-24 CN disclosed
WO-2006063867-A2 SYMMETRICAL DIAZO COMPOUNDS CONTAINING 3-PYRIDINIUM GROUPS AND A NON-CATIONIC LINKER, COMPOSITIONS COMRISISNG THEM, METHOD OF COLOURING, AND DEVICE L'ORÉAL (FR) 2006-06-22 WO disclosed
WO-2006056488-A1 SYMMETRICAL CATIONIC TETRAAZO COMPOUNDS, FOR DYEING KERATIN FIBRES L'OREAL (FR) 2006-06-01 WO disclosed
WO-2006056489-A2 PARTICULAR DISSYMMETRICAL CATIONIC POLYAZO COMPOUNDS, COMPOSITIONS COMPRISING THEM AS DIRECT DYE, PROCESS FOR DYEING KERATIN FIBRES AND DEVICE THEREFOR L'OREAL (FR) 2006-06-01 WO disclosed
EP-1660032-A1 COMPOSITION FOR DYEING HUMAN KERATIN FIBRES, COMPRISING A 1H-PYRAZOLYL-ETHENYL-INDOLIUM DERIVATIVE L'OREAL (FR) 2006-05-31 EP disclosed
WO-2005013929-A1 COMPOSITION FOR DYEING HUMAN KERATIN FIBRES, COMPRISING A 1H-PYRAZOLYL-ETHENYL-INDOLIUM DERIVATIVE L'OREAL (FR) 2005-02-17 WO disclosed