Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14113277 | 0.93 | SPPL2A (0.49) | ABCB1SPPL2ALMNAMLNRABCB11 | |
| SCHEMBL14367269 | 0.92 | SPPL2A (0.46) | ABCB1SPPL2ALMNAMLNRABCB11 | |
| SCHEMBL14113284 | 0.91 | BMP1 (0.46) | ABCB1SPPL2ALMNAMLNRABCB11 | |
| SCHEMBL14367270 | 0.88 | SPPL2A (0.49) | ABCB1SPPL2ALMNAMLNRABCB11 | |
| SCHEMBL14367267 | 0.86 | SPPL2A (0.47) | ABCB1SPPL2ALMNAMLNRABCB11 | |
| SCHEMBL6260176 | 0.84 | BMP1 (0.39) | LMNA | |
| SCHEMBL5403915 | 0.82 | SPPL2A (0.53) | ABCB1SPPL2ALMNAMLNRABCB11 | |
| SCHEMBL14338882 | 0.82 | SPPL2A (0.51) | ABCB1SPPL2ALMNAMLNRABCB11 | |
| SCHEMBL14338852 | 0.81 | SPPL2A (0.48) | ABCB1SPPL2ALMNAMLNRABCB11 | |
| SCHEMBL5863507 | 0.80 | SPPL2A (0.53) | ABCB1SPPL2ALMNAMLNRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | disclosed |
| US-7297793-B2 | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors | G.D. SEARLE, LLC (US) | 2007-11-20 | — | — | US | disclosed |