Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 15/20 | 0.81 |
| ▸ | CNR1 | P21554 | 10/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623108 | 1.00 | CNR2 (0.81) | CNR2CNR1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL14367340 | 1.00 | CNR2 (0.81) | CNR2CNR1TDP1ALDH1A1L3MBTL1 | |
| SCHEMBL14367347 | 0.91 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL5623688 | 0.91 | CNR2 (0.83) | CNR2CNR1 | |
| SCHEMBL14367345 | 0.90 | CNR2 (1.00) | CNR2CNR1ALDH1A1 | |
| SCHEMBL5623613 | 0.90 | CNR2 (1.00) | CNR2CNR1ALDH1A1 | |
| SCHEMBL5623511 | 0.89 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14367422 | 0.89 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL5623432 | 0.89 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14367346 | 0.88 | CNR2 (0.77) | CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7297796-B2 | Sulfamoyl benzamide derivatives and methods of their use | ADOLOR CORPORATION (US) | 2007-11-20 | — | — | US | disclosed |