SCHEMBL14367346

SCHEMBL14367346

CC(C)c1ccc(C(=O)N[C@@H]2C(C)(C)[C@@H]3CC[C@@]2(C)C3)cc1S(=O)(=O)N1CCCCC1

nearest known ligand 0.77

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 18/20 0.77
CNR1 P21554 11/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5623318 1.00 CNR2 (0.77) CNR2CNR1
SCHEMBL5654532 0.91 CNR2 (0.79) CNR2CNR1
SCHEMBL5652113 0.91 CNR2 (0.79) CNR2CNR1
SCHEMBL14367347 0.88 CNR2 (0.83) CNR2CNR1
SCHEMBL14367335 0.88 CNR2 (0.81) CNR2CNR1
SCHEMBL5623108 0.88 CNR2 (0.81) CNR2CNR1
SCHEMBL5623688 0.88 CNR2 (0.83) CNR2CNR1
SCHEMBL14367340 0.88 CNR2 (0.81) CNR2CNR1
SCHEMBL5623613 0.87 CNR2 (1.00) CNR2CNR1
SCHEMBL14367345 0.87 CNR2 (1.00) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7297796-B2 Sulfamoyl benzamide derivatives and methods of their use ADOLOR CORPORATION (US) 2007-11-20 US disclosed
US-7297796-B2 Sulfamoyl benzamide derivatives and methods of their use ADOLOR CORPORATION (US) 2007-11-20 US disclosed