⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631878 | 1.00 | — | — | |
| SCHEMBL14817167 | 1.00 | — | — | |
| SCHEMBL25040378 | 1.00 | — | — | |
| SCHEMBL854100 | 0.83 | — | — | |
| SCHEMBL8320708 | 0.83 | — | — | |
| SCHEMBL12439734 | 0.83 | — | — | |
| SCHEMBL12439541 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL6371160 | 0.80 | LMNA (0.38) | — | |
| SCHEMBL13978786 | 0.80 | — | — | |
| SCHEMBL17779199 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217987-A1 | INHIBITOR COMPOUNDS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2024-07-04 | — | — | US | disclosed |
| WO-2021074620-A1 | [1,4]OXAZEPINO[2,3-C]QUI NOLI NONE DERIVATIVES AS BLC6 INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2021-04-22 | — | — | WO | disclosed |
| US-20070254920-A1 | Prodrug derivatives of acids using alcohols with homotopic hydroxy groups and methods for their preparation and use | AERIE PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |