Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trichlorethanol SCHEMBL325071 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL7261325 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL291748 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL759616 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL8522341 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL16162174 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL4450822 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL88329 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL762332 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR | |
| Trichlorethanol SCHEMBL6898269 | 1.00 | LMNA (0.33) | LMNATDP1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933354-B1 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | KYOWA HAKKO KIRIN CO LTD (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-7816408-B2 | Calcium receptor active compounds | NPS PHARMACEUTICALS, INC. (US) | 2010-10-19 | — | — | US | disclosed |
| US-20090176993-A1 | Calcium receptor active compounds | NPS PHARMACEUTICALS, INC. | 2009-07-09 | — | — | US | disclosed |
| US-6939895-B2 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2005-09-06 | — | — | US | disclosed |
| US-6750255-B2 | SUCH AS (R)-N-(1-(1'-NAPHTHYL)ETHYL)-2-(2',5'-DICHOROPHENYL THIO)ETHYLAMINE; FOR STIMULATION OF SECRETION OF PARATHYROID HORMONE | NPS PHARMACEUTICALS, INC. | 2004-06-15 | — | — | US | disclosed |
| CN-1131202-C | Calcium receptor-active compounds | KIRIN BREWERY (JP) | 2003-12-17 | — | — | CN | disclosed |
| US-20030176485-A1 | Calcium receptor active compounds | NPS PHARMACEUTICALS, INC. | 2003-09-18 | — | — | US | disclosed |
| US-20030144526-A1 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. | 2003-07-31 | — | — | US | disclosed |
| US-20020107406-A1 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2002-08-08 | — | — | US | disclosed |
| US-6362231-B1 | MODULATOR OF PARATHYROID HORMONE; OSTEOPOROSIS | NPS PHARMACEUTICALS, INC. | 2002-03-26 | — | — | US | disclosed |
| EP-0933354-A1 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | KIRIN BEER KABUSHIKI KAISHA (JP) | 1999-08-04 | — | — | EP | disclosed |
| CN-1225083-A | Calcium receptor-active compounds | KIRIN BREWERY (JP) | 1999-08-04 | — | — | CN | disclosed |
| US-4137318-A | HYPOTENSIVES AND HEART RATE REDUCERS | BOEHRINGER INGELHEIM GMBH (DE) | 1979-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144526-A1 | Calcium receptor-active compounds | CASR, CALCR, CNR1 | LMNA 4615/4885TDP1 4852/4885TP53 4765/4885 |
| US-20090176993-A1 | Calcium receptor active compounds | CASR, CALCR, CACNA1E | LMNA 4836/4885TDP1 4799/4885TP53 4031/4885 |
| US-20030176485-A1 | Calcium receptor active compounds | CASR, CNR1, CALCR | LMNA 4704/4885TDP1 4827/4885TP53 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.