Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12827256 | 0.80 | CYP11B1 (0.55) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| SCHEMBL14382237 | 0.77 | HDAC1 (0.53) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| SCHEMBL4652514 | 0.77 | ALOX15 (0.53) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| SCHEMBL4278243 | 0.77 | ALOX15 (0.53) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| SCHEMBL9863750 | 0.77 | ALOX15 (0.53) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| SCHEMBL24784588 | 0.77 | HDAC1 (0.55) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| SCHEMBL5542313 | 0.77 | ALOX15 (0.53) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| SCHEMBL12617050 | 0.76 | HDAC1 (0.53) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| Hydrochloric Acid SCHEMBL9512459 | 0.75 | ALOX15 (0.52) | CYP11B1CYP11B2ALOX15TSHRCASP1 | |
| SCHEMBL10184678 | 0.74 | HDAC1 (0.56) | CYP11B1CYP11B2ALOX15TSHRCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |
| US-7291644-B2 | Indole derivatives | ONO PHARMACEUTICALS CO., LTD. (JP) | 2007-11-06 | — | — | US | disclosed |