Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 13/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13964369 | 0.97 | KDM4E (0.49) | KDM4ECSNK1EATREPHX2NPC1 | |
| SCHEMBL14368383 | 0.91 | NAMPT (0.46) | CSNK1EPOLB | |
| SCHEMBL13964269 | 0.88 | NAMPT (0.49) | KDM4ECSNK1EPOLB | |
| SCHEMBL14368407 | 0.87 | NPC1 (0.50) | KDM4ECSNK1ENPC1RAB9APOLB | |
| SCHEMBL4043909 | 0.86 | CSNK1E (0.47) | CSNK1EPOLB | |
| SCHEMBL13964270 | 0.86 | HTR1F (0.45) | KDM4ECSNK1E | |
| SCHEMBL13964365 | 0.83 | CSNK1E (0.54) | CSNK1ERAB9APOLB | |
| SCHEMBL13963912 | 0.83 | NPC1 (0.51) | KDM4ECSNK1ENPC1RAB9APOLB | |
| SCHEMBL14368388 | 0.83 | CSNK1E (0.53) | CSNK1E | |
| SCHEMBL4038686 | 0.82 | MAPT (0.48) | CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070238734-A1 | JNK INHIBITORS | SANOLI-AVENTIS (FR) | 2007-10-11 | — | — | US | disclosed |
| US-20070238734-A1 | JNK INHIBITORS | SANOLI-AVENTIS (FR) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238734-A1 | JNK INHIBITORS | MAP3K7, MAPKAPK2, MAPK7 | KDM4E 2836/4885CSNK1E 136/4885ATR 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.